What's old is new again
New potential off-label use of tamoxifen

It is common practice for FDA-approved drugs find "new life" through off-label usage. This may be accomplished through the administration of the drug by a different route or using a different dosage but more typically by prescribing the drug for a different indication. Though there are strict guidelines outlined by the FDA before approval for a potential therapeutic, interestingly, off-label use is not regulated and is up to the discretion of physicians. Due to this prescription freedom, upwards of one-fifth of all drugs are prescribed off-label...

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