tag:blogger.com,1999:blog-27520665764315091072024-03-08T16:00:52.726-05:00bio-typingbio-typing covers recent news in biomedical research and the latest discoveries in drug design and development as well as commentary on science-related issuesShalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.comBlogger11125tag:blogger.com,1999:blog-2752066576431509107.post-40701736937102113722009-01-17T14:23:00.011-05:002009-01-17T14:30:55.684-05:00Lily must pay up: pharma and illegal drug promotionI first came to understand the link between the responsibility of pharma to closely follow FDA marketed drug regulations and related pharmaceutical company lawsuits with the landmark Merck settlements. The Vioxx claims of increased cardiac events in patients and the cover-up of data implicating these conditions reminded me of the power Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-78557137864070482562008-12-27T14:48:00.003-05:002008-12-27T15:31:39.451-05:00Efficacy and Safety of Incretin in Type 2 Diabetes
<!--[if gte mso 9]> Normal 0 false false false EN-US X-NONE X-NONE <![endif]--><!--[if gte mso 9]>Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-33929416688550805712008-10-14T12:20:00.004-04:002008-10-14T13:45:42.641-04:00Drug discovery: forward or reverse pharmacology?Drug discovery is a very complex process which entails discovering new agents for the treatment or prevention of diseases and disorders. Despite the high level of advances in the understanding of the human body, from basic human physiology to the smallest level of the human genome, a potential agent still takes an upward of 15 years from Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-8868101940292230962008-09-18T11:47:00.004-04:002008-09-18T11:58:37.511-04:00Sidenotes: Taking a break & In ScriptoI realized the other day that I haven't posted in a month. With everything that is going on with finshing up with school, looking into career opportunites, and freelance writing, I haven't had a chance to update my blog. But I will be back in a couple of weeks with a post about the scientific platforms in politics. I am particularly excited about this Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-64224870409994579502008-08-17T13:34:00.005-04:002008-08-17T16:47:40.453-04:00Science and the Summer Olympics I haven't written a post in almost three weeks. That is because I have been enthralled with all that is the Summer Olympics in Beijing and the phenom that is Michael Phelps. I have been keeping up with him ever since I first got a glimpse of his talent watching the Athens Olympics back in '04. He is awesome. He is amazing. He is definitely the greatest OlympianShalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-30939724143390879902008-07-30T15:07:00.006-04:002008-07-30T15:17:37.768-04:00Patient-funded drug research If you are a biomedical research, scientist, healthcare profression, or just aware of the drug development process than you know how it can take an upwards of 15 years and $1 billion dollars for pharmaceutical companies and smaller biotechs to bring a drug to market. It can cause problems for both patients and the business side of these companies, delaying promising Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-68022580047144577412008-07-05T20:23:00.005-04:002008-07-06T17:21:04.630-04:00Leprosy in film contextSome friends and I started an independent and foreign film club where we get together once a month and watch a "little-known" movie that may have been overlooked and discuss them. This month, the host chose "The Motorcycle Diaries", a film that depicts the early life of Che Guevara and is based on his own written accounts. The movie shows how a simple motorcycle trip he Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-36874518399265562152008-06-25T10:20:00.020-04:002008-07-06T15:36:49.687-04:00The ExpIND and the phase 0 clinical trialI have a deep interest in cancer pharmacology and drug development. My dissertation project involves studying the mechanism of action of a novel analog of the spice curcumin which may be a potential chemotherapeutic in the future. Excitingly, this compound is entering phase 0 clinical trials for head & neck cancer to be led by my PI and research Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-21715162032575236062008-06-11T14:04:00.015-04:002008-06-20T16:14:52.070-04:00What's old is new againNew potential off-label use of tamoxifenIt is common practice for FDA-approved drugs find "new life" through off-label usage. This may be accomplished through the administration of the drug by a different route or using a different dosage but more typically by prescribing the drug for a different indication. Though there are strict guidelines outlined by the FDA before Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-77475457412874759132008-05-26T22:30:00.007-04:002008-06-20T16:18:06.431-04:00It's not really bone marrow donation anymoreI'm just waiting on that call. I can vaguely remember representatives from the National Marrow Donner Program coming to visit my college. They shuffled a group of the premed and science majors in the student center to learn about the technology behind bone marrow donation and the wonderful gift of being a donor. See, the whole purpose of extracting Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0tag:blogger.com,1999:blog-2752066576431509107.post-54441865931866922082008-05-20T22:39:00.012-04:002008-06-20T16:18:16.266-04:00PTEN: linking cancer and autismRecently, the phosphatase and tension homolog (PTEN) gene has been linked to the developmental austism spectrum disorders (ASDs) including Cowden Syndrome (CS). Once only seen as a gene related to tumor development and progression, PTEN has been reported to have increased mutations in children with austim, mental retardation, and macrocephaly or enlarge head size..Shalahttp://www.blogger.com/profile/12810705695582482542noreply@blogger.com0